Live tender

DLSITT1092 - Double Crystal Monochromator for Beamline K04 for Diamond Light Source

DIAMOND LIGHT SOURCE LIMITED · South East · up to £321,000

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What the buyer wants

Supply and install a double crystal monochromator system including cooling, vacuum, and crystal support for the K04 beamline at Diamond Light Source to enhance macromolecular crystallography capabilities.

Located on the Harwell Science & Innovation Campus in Oxfordshire, Diamond Light Source (DLS) is a leading-edge facility for science, engineering and innovation. DLS allows researchers from academia and industry to investigate the structure and behaviour of the world around us at the atomic and molecular level. To continue delivering the world-changing science that Diamond enables, the facility is being upgraded to Diamond-II, a co-ordinated programme of development that combines a major machine upgrade with new instruments and complementary improvements to optics, detectors, sample environment and delivery capabilities, and computing, as well as integrated and correlative methods. This will be transformative in speed and spatial resolution and will offer users streamlined access to enhanced instruments for life and physical sciences.

The K04 beamline will be an ultra-high throughput Macromolecular Crystallography beamline optimised for the study of biological samples (fragment screening) to support the XChem facility in early-stage lead drug discovery. K04 will greatly increase DLS's capacity to carry out XChem experiments by up to 20x, accelerating drug discovery timelines and related research for both the academic community and industrial customers.

The monochromator system shall include the VACCS cooling system (Vacuum Aspirated Cryo Cooling System) and three crystal sets. This full system will be developed in collaboration with engineers at DLS.

The minimum scope of the contract is the design, manufacture, test, delivery, installation and commissioning of:

• A horizontally deflecting, asymmetric cut, double crystal monochromator (DCM)

• The crystal sets and interfaces with DLS-designed cooling system(s)

• Vacuum system in line with DLS Vacuum requirements

• Crystal support and manipulation system

• Interfacing with beamline services.

See specification for further details.

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